Research and Development
PLM 추출액은 세포독성이 거의 없음
PLM 추출물은 저분자로 투명한 compound인 반면, 열수 추출물은 고분자로 다량의 compound임


Figure. Inhibitory effect of BBA on TPA-induced ear edema. The ears of mice in each group were treated with TPA (1 μg/ear) once a day for 3 days. BBA (10-50 mg/Kg) was topically applied to mice ears 1 h after TPA treatment for 3 days. Inhibition of TPA-induced ear edema by topical application of BBA was analyzed by measuring (A) morphological changes in ear weight (B) and ear thickness (B). Data are represented as the means ± SD of 3 independent experiments. ### P < 0.001 compared with Control; *** P < 0.01; ** P < 0.01; * P < 0.05 compared with TPA.


Figure. Inhibitory effect of BBA on TPA-induced inflammatory markers in mice ears. Mice ears (five mice in each group) were treated with TPA (1 μg/ear) once a day for 3 days. BBA (10-50 mg/Kg) was topically applied to mice ears 1 h after TPA treatment for 3 days. Mice ear extracts were prepared and analyzed for TPA-induced inflammatory markers protein expression (A). The densitometry analysis of inflammatory markers (B). ### P < 0.001 compared with Control; *** P < 0.01; ** P < 0.01; * P < 0.05 compared with TPA.





